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Disclaimer: These studies are not studies involving the Treatibles products. We at Treatibles do not make any claims that our products will treat or cure these ailments. Third party empirical studies of Treatibles have not yet been conducted. We are providing these links purely as an educational resource.


Depression

2010 - Study: Antidepressant-like effects of cannabidiol in mice: possible involvement of 5 HT receptors
2010 - Antidepressant-like effect of Delta (9)-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa

Anxiety

2010 - Study: Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal mode of mania
2010 - Therapeutical use of the cannabinoids in pyschiatry
2010 - A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice
2010 - Neural bliss of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
2011 - Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress
2011 - Cannabidiol potentiates Delta(9)-tetrahydrocannabinol (THC) behavioral effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats
2011 - Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients
2011 - Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
2011 - The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives
2012 - Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug
2012 - On disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment


Seizures

2010 -  Anticonvulsant effects of GWP42006 in vitro and in vivo in rat
2010 -  Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo. 
2012 -  Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.

Memory

2010 - Key ingredient staves off marijuana memory loss.
2010 - Key ingredient dilutes marijuana's effect on memory.
2010 - Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study

Brain Damage

2010 -  Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke.
2010 -  Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania.
2010 -  Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation
2010 -  Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology
2010 -  Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry
2010 -  Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture
2010 -  The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors
2010 -  Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis
2011 -  Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs

Parkinson's Disease

2010 - Brazilian Scientists Show How Marijuana Can Help in Treating Parkinson

Alzheimer's Disease & Dementia

2011 -  Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers' disease
2011 -  US Patent Application 20110257256 - CANNABINOIDS FOR USE IN TREATING OR PREVENTING COGNITIVE IMPAIRMENT AND DEMENTIA
2011 -  Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders
2011 -  Prospects for cannabinoid therapies in basal ganglia disorders
2011 -  Phytocannabinoids as novel therapeutic agents in CNS disorders
2011 -  Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders
2012 -  The therapeutic potential of the endocannabinoid system for Alzheimer's disease
2012 -  Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid


Breast Cancer

2011 - Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis
2011 - Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy

Cancer Cells

2010 - Antitumorigenic Effects of Cannabinoids beyond Apoptosis
2010 - Anti-tumoural effects of cannabinoid combinations - Patent TW201002315 (A)
2010 - Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases
2010 - Cannabidiol Enhances the Inhibitory Effects of Delta9 - Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival
2010 - Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity
2010 - Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of efficacy, safety, and tolerability of THC
2011 - Phytocannabinoids for use in the treatment of cancer - Patent GB2478595(A) 
2011 - Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes
2012 - Cannabidiol Inhibits Angiogenesis by Multiple Mechanisms
2012 - Poly-e-caprolactone microspheres as a drug delivery system for cannabinoid administration: Development characterization and in vitro evaluation of their antitumoral efficacy2012 - Cannabidiol-induced apoptosis in murine microglial cells through lipid raft

Lung Cancer

2010 -  Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells.

Brain Cancer

 2010 - Science: Cannabidiol enhances the anti-cancer effects of THC on human brain cancer cells.

Colon Cancer

2011 -  Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent 
2012 -  Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
2010 -  Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain.
2010 - Cannabinoids inhibit and may prevent neuropathic pain in diabetes.
2012 -  Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.





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